Creatinase(creatine amidinohydrolase,EC 3.5.3.3)catalyzes the hydrolysis of creatine to sarcosine and urea.

肌酸水解酶(EC 3.5.3.3)是肌氨酸氧化酶法测定肌酐含量方法中的关键酶,与肌酐水解酶和肌氨酸氧化酶催化肌酐的降解。

There are three critical enzymes(creatininase,EC 3.5.2.10;creatinase,EC 3.5.3.3;sarcosine oxidase,EC 1.5.3.1) generally used in the enzymatic measurement system. Among these enzymes the creatinase is a very important one,which catalyzes the hydrolysis of creatine to form sarcosine and urea.

酶法所用的工具酶主要有三种(肌酐酶,EC 3.5.2.10;肌酸酶,EC 3.5.3.3;肌氨酸氧化酶,EC 1.5.3.1),肌酸酶是其中非常重要的一种,主要来源于微生物,但在我国目前尚不能自主生产。