This text combines for tutor’s few years of clinical experience, select by examinations the chronic renal failure within insufficiency of both the spleen and the kidney in 30, with the yin and yang repairs with each other for method, draft "Four flavors leak muddy soup" treatment, prognosticate it to combine dint, serum creatinine , serum urea nitrogen, urine egg white and wet the function of occult blood to the blood-red cell, blood plasma egg white, ion, carbon dioxide, observe to clarify the function mechanism that it protects kidney to improvement function and first step of kidney function thus, with "The kidney healthy and peaceful slice" conduct and actions check against to compare, it total efficient is 86.67%, the curative effect shows prominence (P<0.05) better than matched control, "Four flavors leak muddy soup" various clinical symptom that the muddy soup can improve chronic renal failure obviously and various physics and chemistry check index sign, this learns to the chronic renal failure in the doctor didn’t yet special effect of today of treatment method, express a Chinese medicine well the advantage of the under medical treatment at the difficulty disease, have the value of thorough research.

本文结合导师数年的临床经验，选取慢性肾衰之脾肾阳虚候60例，以阴阳互补为法，拟定四味泄浊汤治疗，观测其对血红细胞、血浆蛋白、离子、二氧化碳结合力、血清肌酐、血清尿素氮、尿蛋白、尿潜血的作用，从而观察对肾功能的改善作用及初步阐明其保护肾脏的作用机制，与肾康宁片作为对照相比，其总有效率为86.67％，疗效显著(P＜0.05)优于对照组。 四味泄浊汤能明显改善慢性肾衰的各种临床症状及各项理化检查指标，这在西医学对慢性肾衰还没有特效的治疗方法的今天，充分表明了中医药在疑难病治疗中的优势，具有深入研究的价值。