Combination of algae cells in the light micrographs, TEM micrographs and physiological and biochemical research, the inhibition mechanism on the algae of prodigiosin has been studied. The result shows that prodigiosin does harm to membrane of microalgae.
结合赤潮藻细胞显微结构、超微结构的观察及生理生化研究,分析灵菌红素对微藻的抑制机理,结果表明:灵菌红素抑藻作用主要是通过对藻细胞膜系统造成伤害从而抑制藻类的生长。
参考来源 - 海洋弧菌SThe acute and the chronic toxicity of prodigiosin in mice was observed.
观察动物口服灵菌红素的急性毒性和长期毒性反应。
参考来源 - 新疆块根芍药（Paeonia anomala）内生菌的分离、XJUProdigiosin arrested LS174t cells in S-phase. The results showed that prodigiosin can induce the apoptosis of LS174t and may be mediated by down-regulation of Bcl-2 and up-regulation of Bax.
表明灵杆菌素能有效地通过诱导凋亡抑制LS174t细胞生长,其机制可能与抑制抗凋亡因子bcl-2的表达,增强凋亡因子bax的表达有关。
参考来源 - 灵杆菌素分离纯化及其抑制肿瘤细胞增殖的研究