verapamil SR缓释剂;维拉帕米缓释剂
VERAPAMIL HYDROCHL盐酸维拉帕米
Verapamil HCl盐酸维拉帕米;盐酸异博定;产品
Verapamil HClCAS盐酸维拉帕米
verapamil tablet维拉帕米片
DR verapamil缓释异博定
Verapamil Hydrochloride盐酸维拉帕米;维拉帕米盐酸盐;维拉帕米;异博定
Verapamil Weilapami盐酸维拉帕米
VERAPAMIL HYDROCHLORIDECAS盐酸维拉帕米
The inhibitors, cyclosporine A and verapamil,significantly enhanced the uptake amount of 9-nitrocamptothecin (. P<0.05) .
P-糖蛋白抑制剂维拉帕米能显著增加各段小肠对9-NC的吸收(P<0.05),在小肠下端更加明显。
ALL the five drugs, retinoic acid, tamoxifen, indometacin,verapamil and octreotide, enhanced the inhibition ability of antitumordrugs to both primary cells and PANG-i cell lines.
乃)维甲酸,三苯氧胺,异搏定可以增加阿霉素在PANC习细胞内积聚。
参考来源 - 胰腺癌化疗药敏及增敏的实验研究The results showed that PI-PLC activities were decreased in the tumor cells after treated with verapamil. These changes occurred simultaneously with those changes indexes of calcium homeostasis.
结果表明经异搏定处理后的A_2细胞PI-PLC活性显著降低,并与钙恒稳的指标基本呈现相应的平行变化趋势。
参考来源 - 异搏定对小鼠肝癌腹水瘤细胞系PIMDR results showed that compounds 7 and 10 exhibited moderate reversal activities,and were slightly less potent than those of verapamil against K562 cell line. It is believed that compounds 7 and 10 have MDR activity.
结果和结论:化合物的结构均由核磁共振氢谱,质谱,红外和元素分析确证,活性实验结果显示,化合物7,10逆转活性略低于维拉帕米,但是仍具有一定的多药耐药逆转活性。
参考来源 - 1N(名词) a calcium-channel blocker used in the treatment of angina pectoris, hypertension, and some types of irregular heart rhythm 戊酸丙胺; 一种治疗心脏疾病的药物 [医学]