From veratraldehyde, the overall yield of moexipril hydrochloride is 21.6% as reported.

文献报道总收率为21.6％(以藜芦醛计)。

The optimal reaction conditions were n(diethyl malomate)∶n(veratraldehyde)=2.0∶1.0,n(L-proline)∶n(veratraldehyde)=0.35∶1.00,n(L-proline)∶n(potassium phosphate)=6∶1,and reacting for 7 h,The yield of ethyl 3,4-dimethoxycinnamate was 77.4% with 97.0% purity.

实验得到较佳反应条件:n(丙二酸二乙酯)∶n(黎芦醛)=2.0∶1.0,n(L-脯氨酸)∶n(黎芦醛)=0.35:1.00,n(L-脯氨酸)∶n(磷酸钾)=6∶1,反应时间7 h。 在较佳条件下,3,4-二甲氧基肉桂酸乙酯的收率达到77.4%,质量分数达97.0%。